As quickly as ephedra came onto the market as a weight loss solution, it was taken off. The manufacturers are not deterred, as they have been rabidly replacing the products with ephedra free ingredients. So what do they contain and do they work?
A study of ephedra free weight loss dietary supplements containing bitter orange (citrus aurantium), a botanical source of the adrenergic amines synephrine and octopamine was conducted by the Division of Clinical Pharmacology and Experimental Therapeutics Department of Medicine at the University of California in San Francisco. While only a very small quantity of people (10), the conclusion drawn: Ephedra free weight loss supplements have significant cardiovascular stimulant actions, similar to ephedra. These effects are not likely caused by citrus aurantium alone because an eightfold higher dose of synephrine (Advantra Z) had no effect on blood pressure, but may be attributable to caffeine and other stimulants in the multi-component formulation.
It seems that the ephedra free weight loss products increased blood pressure and heart rate, in the same manner that the ephedra products did. This is a red flag to anyone with additional medical problems.
If you are thinking about adding any weight loss supplements or products to your dietary regiment, consult with your primary physician first to make sure you are in a health condition to take them. Working with your primary medical provider will also help to ensure you make the right choices and there aren't any reactions or interactions with current drugs, OTC or other alternative therapies that you are taking.
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