Telostatin

Telostatin™ (U.S. patent # 6,376,557) is the product of a deliberate investigation into the chemical signals that control the hair growth cycle. The application of these findings through our advances in peptide biochemistry offers a new beginning in hair restoration technology for both men and women.

Telostatin is the first and only product in its class to directly stimulate the Anagenic Growth phase of the hair cycle with growth promoting growth factors for hair. The product is also first in its class to directly suppress the Catagenic Rest and Telogenic Loss phases of the hair cycle. The combined result is a hair restoration product that offers faster results with improved efficacy in problem treatment areas.

Additional research focused on the hair growth cycle, with attention to the factors that create a hostile environment for hair maintenance and robust growth. Seborrhea and the scalp parasite Demodex are common stressors that are known to contribute to hair loss. Increasing the blood supply at the hair root has been shown to provide a nutrient-rich environment that favors hair growth. Each consideration has been addressed in the development of Telostatin.

CLINICAL TRIAL
Male volunteers between 26 and 50 years of age with moderate degrees of hair loss were enrolled in a 12-week study conducted by independent physicians. Telostatin was applied was applied one time daily for 12 weeks.

HAIR GROWTH CYCLE
Hair cycle analysis was assessed by special photographic enlargements of a representative area of active hair loss, and subjected to computer analysis. At 8 weeks, 100% of men treated with Telostatin experienced an increase in hair growth and an average 80% reduction in hair loss. Volunteer self-assessment yielded comparable results.

After twelve weeks, hair thickness increased by 69%, while the hair regrowth rate increased 33%. Regrowth Rate combines changes in hair count, hair thickness and hair growth into one value.

ALL study participants with self-described "thin hair" categorized their hair as thicker at trial end.

SEBORRHEA
Seborrhea is a disease of the sebaceous gland that results in a change in the quality and amount of the gland’s secretions, called sebum. The oily coating, crusts or scales that develop on the scalp create a hostile environment for hair growth and can be a significant cause of hair loss in many individuals. Twelve weeks of study revealed a 62% reduction in sebum production for volunteers using Telostatin.

DEMODEX
Of the two types of human Demodex parasites, the one that lives in the sebaceous glands of the scalp can contribute to hair loss. When the Demodex population is low, the parasite has no significant impact on hair loss. But as the population increases, Demodex’s impact on the sebaceous gland’s ability to function creates an overly dry and hostile environment that favors hair loss.

Telostatin, with colloidal sulfur, promotes hair maintenance by controlling the Demodex population. Research findings prove that Telostatin reduces the Demodex population by an average of 32%.

VERTEX STUDY RESULTS
Standardized photographs were rated by an independent physician/panel for an increase or decrease in scalp hair. No participants were found to show a visible decrease in scalp hair.

The photographs below are of a clinical study subject who demonstrated excellent results after using Telostatin for 12 weeks.

Head To Head Comparison

Comment: DHT, or dihydrotestosterone, is the principal cause of male pattern baldness, otherwise known as androgenetic alopecia. Research suggests that DHT at the hair follicle suppresses the release of growth factors needed for hair growth and maintenance. Continued exposure to DHT in predisposed individuals leads to gradual thinning and loss of hair. Removal of DHT from the hair follicle provides for indirect suppression of the telogenic, and to a lesser extent, the catagenic phase of the hair cycle.

LABEL INFORMATION

Directions: Shake bottle vigorously for 30-60 seconds. Apply to fingertips, then directly onto target area of scalp, 1-2 hours before bedtime to provide sufficient time for scalp to absorb the product. Rub scalp with fingertips vigorously for 2-3 minutes. Wash hands directly following application. Allow product to remain on scalp for at least four hours before washing hair. Telostatin should be used on a daily basis. This bottle provides approximately 30-45 applications.

Caution:
•For external use only.
•Avoid contact with the eyes. If contact does occur, rinse eyes thoroughly with cool water.
•Discontinue use if irritation or rash appears

Ingredients: De-ionized Water, Algae Extract, Phenoxyethanol, Propylene Glycol, Glycerin, Margosa, Hydrolysate of Milk Protein, Solanum Tuberosum Extract, Silanediol Salicylate, Butylene Glycol, Triethanolamine, Sulphured Amino Acid, Sulfomucopolysaccharide Extract, Celastrus Paniculata Extract, Colloidal Sulphur, Spondios Amara Extract, Rubus Bramble Berries, Trichomonus Japonicum Maxim, Chinese Wormwood Extract, Homotaurine, Maiden Hair Fern Extract, Henna Extract, Barosma Betulina, Sodium Benzoate, Potassium Sorbate, Polypeptide (Leucine, Proline, Lysine, Glutamine, Aspartic Acid, Metionin, Alanine)

TELOSTATIN™
Frequently Asked Questions

Who should not use Telostatin?
Telostatin should not be used by people less than 18 years of age. People with nutritional deficiencies or medical conditions that require the use of medications that cause hair loss may not benefit from the use of Telostatin. Persons with damaged hair from hair care products or harsh grooming practices may not benefit from the use of Telostatin.

Will Telostatin work for me?
Each person using Telostatin will experience a different amount of hair regrowth and decreased hair loss. To ensure that the product has the opportunity to work, make sure that Telostatin is massaged into the scalp with each application. People with little hair loss and those who are beginning to experience hair loss will likely have a better response than people with long-standing hair loss.

How soon can I expect results from using Telostatin?
Results are twofold: hair regrowth and hair retention. Some people may notice a substantial decrease in hair loss with minimal hair regrowth, and vise versa. Others may notice substantial hair regrowth and decreased hair loss. There is no way to predict who will experience which effect. It is important to remember that hair grows only 1/2 to 1 inch per month, so noticeable hair regrowth will occur slowly. When using the product as directed, most people will first notice a decrease in hair loss and some visible hair regrowth within three months. For other people, visible changes in hair regrowth may take up to six months.

Can I use Telostatin to prevent hair loss?
Yes. Studies have revealed a noticeable decrease in hair loss with continuous use. Since the loss of between 50 to 100 hairs per day is normal, and more is typical of thinning hair, Telostatin should reduce hair loss numbers to within 50 to 100 hairs per day with continuous use as directed. It is unlikely that Telostatin will stop all hair loss.

If Telostatin is stimulating hair regrowth, what will the new hair look like?
New hair growth will first be soft, thin and downy-like. With continued use, this new hair should resemble the rest of the hair on your scalp. Existing hair on the scalp that has been thinning will gradually become thicker.

What will I first notice when I start to use Telostatin?
You will first notice a decrease in hair loss as the product re-regulates the hair cycle. You may wish to monitor this progress by trapping hair as it sheds in the shower and counting the shed hair on a daily basis.

How long do I have to use Telostatin?
If you notice hair regrowth or decreased hair loss, you will have to use Telostatin continuously in order to maintain your new hair growth.

What happens if I completely stop using Telostatin? Will I keep the new hair?
You will need to use Telostatin continuously in order to keep your new hair growth and optimize hair retention. If you stop using Telostatin, new hair will begin to fall out in 3 to 4 months as the hair cycle is completed.

When do I use Telostatin?
Apply two to four hours before going to bed. This will allow Telostatin to dry on the scalp.

How long will one bottle of Telostatin last?
The product is supplied in a 4 ounce bottle. Each bottle should last 30-45 days when used as directed.

What if I forget to use Telostatin?
If you miss an application, simply resume your regular nightly application.

Can I use Telostatin more than once daily? Will it work faster, better?
There is no benefit to using the product more than once daily. It will not work faster or better.

Can I apply Telostatin and wash my hair an hour later?
No. For best results, you should allow four hours for the product to dry on the scalp.

What kind of shampoo should I use with Telostatin?
You may use any kind of shampoo.

Can I use hair sprays, mousses, conditioners, gels, etc?
Yes.

Can I have my hair colored or permed or use hair relaxers while using Telostatin?
You may color or perm your hair. However, you should be aware that Telostatin will not prevent hair loss caused by hair or scalp damage that may occur with these processes. You should not use hair relaxers. The residual chemicals left behind from the relaxing process will denature the product’s active ingredients.

Can Telostatin produce unwanted hair growth?
Unwanted hair growth on the face and body has not been reported. If you notice unwanted hair growth, you may decrease the amount of the product that you apply to the scalp or the frequency of product application. You should also take care to wash your hands after application.

Can I use Telostatin for baldness or hair loss in babies or children?
No. The causes of baldness and hair loss in babies and children are different from the causes of hair loss in adult men and women.

Can I use Telostatin in combination with other hair rejuvenation products?
Yes. You may use Telostatin in combination with Propecia.

What are the most common side effects?
Some people experience itching of the scalp.

Is there a patent on the formulation in Telostatin?
Yes. The patent number is 6,376,557.